Thermo Fisher Scientific HUNK Polyclonal Antibody
HUNK 단백질을 인식하는 Rabbit Polyclonal 항체로 Western blot, IHC, ICC, IP 등 다양한 실험에 사용 가능. Human에 반응하며 항원 친화 크로마토그래피로 정제됨. 단기 4°C, 장기 -20°C 보관 권장.
- 카탈로그번호
- PA528765
- 판매단위
- pk
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:3,000 | View 2 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 | - |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 | - |
| Immunoprecipitation (IP) | – | View 1 publication |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to a region within amino acids 650–714 of Human HUNK (UniProt ID: P57058-1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.65 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1 M Tris glycine, pH 7, with 10% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2546241 |
Product Specific Information
- Recommended positive controls: A431, HeLa
- Predicted reactivity: Chimpanzee (100%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
HUNK (Hormonally Up-regulated Neu-associated Kinase) is a serine/threonine kinase belonging to the mitogen-activated protein kinase family, essential for mammary tumor metastasis.
HUNK deletion in mice does not affect viability, fertility, or tumor development and is dispensable for murine development.
It participates in vesicular transport and regulates endocytosis via interaction with rabaptin-5 protein.
HUNK expression has been observed in mouse brain, breast, embryo, and fetus, and ESTs have been identified in several human tissue libraries, including normal ear.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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