Thermo Fisher Scientific mGluR3 Polyclonal Antibody
Rabbit polyclonal antibody targeting human mGluR3 for WB and ICC/IF applications. Detects mouse, rat, and bovine homologs. Supplied as unconjugated liquid, 0.95 mg/mL. Ideal for neuroscience research on metabotropic glutamate receptors.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:3,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to a region within amino acids 815–879 of Human mGluR3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.95 mg/mL |
| Storage conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2546243 |
Product Specific Information
- Recommended positive controls: 293T, A431, mouse brain, rat brain
- Predicted reactivity: Mouse (100%), Rat (100%), Bovine (100%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Glutamate is the main excitatory neurotransmitter in the brain. It acts on ligand-gated receptor channels such as NMDA, AMPA, and kainate receptors involved in fast excitatory synaptic transmission.
Recently, glutamate has been shown to regulate enzymes producing second messengers via G-protein–coupled receptors, called metabotropic glutamate receptors (mGluRs).
Group-I receptors (mGluR1a, mGluR5) stimulate phospholipase C and increase phosphoinositide turnover and calcium release.
Group-II and -III receptors (including mGluR2 and mGluR3) inhibit adenylyl cyclase activity.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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