Thermo Fisher Scientific KCNMA1 Polyclonal Antibody
KCNMA1 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 IHC(P) 실험에 적합합니다. 인간, 마우스, 랫트 시료에 반응하며, 친화 크로마토그래피로 정제되었습니다. 액상 형태로 제공되며 -20°C에서 보관합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human KCNMA1 (Accession Q12791), corresponding to amino acid residues S778–L828 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2852515 |
Product Specific Information
Antibody detects endogenous levels of total MaxiK alpha.
Target Information
Potassium channels are ubiquitously expressed proteins that serve multiple functions in excitable and non-excitable cells. The large conductance, calcium-activated potassium channel (Maxi K⁺) is controlled by both intracellular calcium increases and membrane depolarization. Its structure includes a voltage sensor and an intracellular calcium-binding domain. In vascular smooth muscle, a beta-subunit associates in a 1:1 ratio, reducing the calcium concentration required to open the channel by 5–10 fold.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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