ELK Biotechnology FA9 (heavy chain, Cleaved-Val227) rabbit pAb

제품명

FA9 (heavy chain, Cleaved-Val227) rabbit pAb

공급업체

ELK Biotechnology

제품 개요

이 항체는 인간 FA9 (heavy chain, Cleaved-Val227)에서 유래한 합성 펩타이드로 면역화된 rabbit polyclonal antibody입니다. 비타민 K 의존성 응고 인자 IX 연구에 적합하며, WB 및 ELISA 분석에 활용할 수 있습니다.

제품 스펙

Background

This gene encodes a vitamin K-dependent coagulation factor IX that circulates in the blood as an inactive zymogen. It is activated by factor XIa, which excises the activation peptide, generating a heavy and a light chain linked by disulfide bonds. Activated factor IX plays a key role in converting factor X to its active form through interactions with calcium ions, membrane phospholipids, and factor VIII. Mutations or deletions in this gene cause factor IX deficiency, known as hemophilia B or Christmas disease. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing. (RefSeq, Sep 2015)