Thermo Fisher Scientific Cytokeratin 16 Polyclonal Antibody
Cytokeratin 16을 검출하는 Rabbit Polyclonal Antibody로, WB, IHC, ICC/IF 등에 사용 가능. 인간, 마우스, 랫트 반응성. Affinity chromatography로 정제된 액상 형태, PBS/glycerol buffer에 보존. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human KRT16 (Accession P08779), corresponding to amino acid residues Q431–S473 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2818105 |
Product Specific Information
Antibody detects endogenous levels of total Cytokeratin 16.
Target Information
KRT16 is a member of the keratin gene family. Keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most type I cytokeratins are acidic proteins arranged in pairs of heterotypic keratin chains and clustered in chromosome region 17q12–q21.
This keratin is coexpressed with keratin 14 in several epithelial tissues, including esophagus, tongue, and hair follicles. Mutations in this gene are associated with type 1 pachyonychia congenita, non-epidermolytic palmoplantar keratoderma, and unilateral palmoplantar verrucous nevus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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