Thermo Fisher Scientific mGluR2/mGluR3 Polyclonal Antibody
mGluR2/mGluR3 단백질을 인식하는 Rabbit Polyclonal 항체로, WB 및 IHC(P) 응용에 적합. 인간, 마우스, 랫트 반응성. 합성 펩타이드 면역원 기반으로 제작. 액상 형태, -20°C 보관, 연구용 전용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:3,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human GRM2 (Accession Q14416), corresponding to amino acid residues I687–L737 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2818101 |
Product Specific Information
Antibody detects endogenous levels of total mGluR2/3.
Target Information
The mGluR proteins (metabotropic Glutamate Receptors) are members of the G-protein-coupled receptor family and are functionally and pharmacologically distinct from the GluR proteins (ionotropic Glutamate Receptors).
The eight currently known mGluR proteins are mediated by two G-proteins with opposing regulation of adenylate cyclase pathways.
The activities of mGluR1 and mGluR5 are mediated by a G-protein that activates a phosphatidylinositol-calcium second messenger system and generates a calcium-activated chloride current.
The remaining mGluR sub-types have activity mediated by a G-protein that inhibits adenylate cyclase activity.
mGluR-3, which may interact with GRASP, acts as a receptor for glutamate.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
- PA5-99168_mGluR2mGluR3_Q14416-1_Rabbit.svg
- PA5-99168_mGluR2mGluR3_Q14416-1_Rabbit_PDP.jpeg
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