Thermo Fisher Scientific PAICS Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

Immunocytochemistry (ICC/IF)

1:10-1:100

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 176-425 of human PAICS (NP_0010729921) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:PAICS,uniProtId:P22234-1,ncbiNodeId:9606,antigenRange:176-425,antigenLength:425,antigenImageFileName:PA5-92985_PAICS_P22234-1_Rabbit.svg,antigenImageFileNamePDP:PA5-92985_PAICS_P22234-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

2.64 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2806573

Product Specific Information

Immunogen sequence: LEKSWLPQNC TLVDMKIEFG VDVTTKEIVL ADVIDNDSWR LWPSGDRSQQ KDKQSYRDLK EVTPEGLQMV KKNFEWVAER VELLLKSESQ CRVVVLMGST SDLGHCEKIK KACGNFGIPC ELRVTSAHKG PDETLRIKAE YEGDGIPTVF VAVAGRSNGL GPVMSGNTAY PVISCPPLTP DWGVQDVWSS LRLPSGLGCS TVLSPEGSAQ FAAQIFGLSN HLVWSKLRAS ILNTWISLKQ ADKKIRECNL; Positive Samples: Jurkat, 293T, SW620, Raji, HeLa

Target Information

This gene encodes a bifunctional enzyme containing phosphoribosylaminoimidazole carboxylase activity in its N-terminal region and phosphoribosylaminoimidazole succinocarboxamide synthetase in its C-terminal region. It catalyzes steps 6 and 7 of purine biosynthesis. The gene is closely linked and divergently transcribed with a locus that encodes an enzyme in the same pathway, and transcription of the two genes is coordinately regulated. The human genome contains several pseudogenes of this gene. Multiple transcript variants encoding different isoforms have been found for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.