Thermo Fisher Scientific NRBF2 Polyclonal Antibody
NRBF2 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western blot, IHC, ICC/IF, ELISA에 적합합니다. Human, Mouse, Rat 시료에 반응하며, 세포질 및 핵 내 NRBF2 단백질 검출에 유용합니다. Affinity Chromatography로 정제된 고순도 항체입니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing amino acids 1–287 of human NRBF2 (NP_1103862) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.03 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2806576 |
Product Specific Information
Immunogen sequence:
MEVMEGPLNL AHQQSRRADR LLAAGKYEEA ISCHKKAAAY LSEAMKLTQS EQAHLSLELQ RDSHMKQLLL IQERWKRAQR EERLKAQQNT DKDAAAHLQT SHKPSAEDAE GQSPLSQKYS PSTEKCLPEI QGIFDRDPDT LLYLLQQKSE PAEPCIGSKA PKDDKTIIEE QATKIADLKR HVEFLVAENE RLRKENKQLK AEKARLLKGP IEKELDVDAD FVETSELWSL PPHAETATAS STWQKFAANT GKAKDIPIPN LPPLDFPSPE LPLMELSEDI LKGFMNN
Positive Samples: SKOV3, HepG2, 293T, HeLa, Jurkat, Mouse brain, Mouse heart, Rat brain
Cellular Location: Cytoplasm, Cytoplasmic vesicle, Nucleus, Autophagosome
Target Information
NRBF2 (Nuclear Receptor-Binding Factor 2) modulates transcriptional activation by target nuclear receptors. It is involved in starvation-induced autophagy through association with PI3K complex I (PI3KC3-C1). NRBF2 stabilizes the PI3KC3-C1 assembly and enhances ATG14-linked lipid kinase activity of PIK3C3.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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