Thermo Fisher Scientific SUR1 Monoclonal Antibody (N289/16)
SUR1 단백질을 인식하는 Mouse IgG1 단일클론 항체로, WB, IHC, ICC/IF에 사용 가능. Rat SUR1 C-말단(aa 1548-1582) 융합단백질을 면역원으로 제작. 단백질 G 정제, PBS + 50% glycerol에 보관, -20°C 저장. 약 160kDa 밴드 검출, SUR2B와 교차반응 없음.
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Thermo Fisher Scientific SUR1 Monoclonal Antibody (N289/16)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1:100 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Hamster, Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | N289/16 |
| Immunogen | Fusion protein amino acids 1548–1582 (cytoplasmic C-terminus) of rat SUR1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2735378 |
Available Conjugated Formats
Product Specific Information
- 1 µg/mL of MA5-27660 detects SUR1 in 20 µg of mouse brain membrane lysate by colorimetric immunoblot using goat anti-mouse IgG:HRP as secondary antibody.
- Detects approximately 160 kDa.
- Does not cross-react with SUR2B.
- This antibody was formerly sold as clone S289-16.
Target Information
The protein encoded by this gene is a member of the ATP-binding cassette (ABC) transporter superfamily. ABC proteins transport various molecules across cellular membranes and are divided into seven subfamilies. This protein belongs to the MRP subfamily, involved in multi-drug resistance. It modulates ATP-sensitive potassium channels and insulin release.
Mutations and deficiencies in this protein are linked to hyperinsulinemic hypoglycemia of infancy and non-insulin-dependent diabetes mellitus type II. Alternative splicing has been observed, but transcript variants are not fully characterized.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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