Thermo Fisher Scientific MED14 Polyclonal Antibody

Thermo Fisher Scientific MED14 Polyclonal Antibody

Applications

• Western Blot (WB)

Tested Dilution: 0.1–0.5 µg/mL

Species Reactivity

• Human
• Mouse
• Rat

Host / Isotype

• Rabbit / IgG

Class

• Polyclonal

Type

• Antibody

Immunogen

E. coli-derived human MED14 recombinant protein (Position: D181–D375)

Conjugate

• Unconjugated

Form

• Lyophilized

Concentration

• 500 µg/mL

Purification

• Antigen affinity chromatography

Storage Buffer

• PBS with 4 mg trehalose

Contains

• 0.05 mg sodium azide

Storage Conditions

• −20°C

Shipping Conditions

• Wet ice

RRID

• AB_2746770

Product Specific Information

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.

Target Information

The activation of gene transcription is a multistep process triggered by factors recognizing transcriptional enhancer sites in DNA. These factors cooperate with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus.
The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. It is also a component of other multisubunit complexes such as thyroid hormone receptor (TR)-associated proteins that interact with TR and facilitate TR function on DNA templates. This protein contains a bipartite nuclear localization signal and is known to escape chromosome X-inactivation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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