Thermo Fisher Scientific PROZ Monoclonal Antibody (OTI4D5), TrueMAB
인간 PROZ 단백질을 인식하는 마우스 단클론 항체로, IHC(P)에서 1:150 희석으로 사용 가능. 비결합형 액상 형태이며, 고순도의 친화 크로마토그래피 정제 제품. 연구용으로만 사용되며, 혈액 응고 관련 단백질 연구에 적합.
- 판매단위
- pk
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4D5 |
| Immunogen | Human recombinant protein fragment (aa 115–400 of human PROZ) produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
PROZ (Protein Z) is a vitamin K-dependent plasma glycoprotein (62 kDa, 396 amino acids). It contains four domains: a Gla-rich region, two EGF-like domains, and a trypsin-like domain. Although structurally related to serine proteases (factors VII, IX, X, and protein C), it lacks catalytic serine residue and is inactive enzymatically. PROZ functions as part of the coagulation cascade, facilitating degradation of factor Xa via protein Z-related protease inhibitor (ZPI). Deficiency may be linked to thrombosis or bleeding tendencies. Its activity is impaired under warfarin therapy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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