Thermo Fisher Scientific PDCD1 Monoclonal Antibody (OTI15B5), TrueMAB
인간 PDCD1 단백질을 인식하는 마우스 단클론 항체로, Flow Cytometry에 적합합니다. 고순도의 Affinity chromatography 정제 제품이며, 1 mg/mL 농도의 액상 형태로 제공됩니다. 면역억제 수용체 PD-1 연구에 유용합니다.
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- TA807847
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- pk
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Applications
- Flow Cytometry (Flow)
Tested Dilution: 1:50
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI15B5 |
| Immunogen | Full length human recombinant protein of human PDCD1 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Cell-mediated immune responses are initiated by T lymphocytes that are stimulated by peptides bound to MHC molecules on antigen-presenting cells (APCs). T-cell activation is self-limited as activated T cells express inhibitory receptors such as PD-1 (also known as PDCD-1). PD-1 binds to ligands PDL-1 and PDL-2, generating inhibitory signals that suppress immune activation in the absence of danger signals. PD1-deficient mice exhibit hyperactivated immune systems and autoimmune diseases. Despite its predicted molecular weight, PD-1 often migrates at a higher molecular weight in SDS-PAGE.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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