Thermo Fisher Scientific NeuroD1 Monoclonal Antibody (8C4H4)
NeuroD1 단백질을 인식하는 Mouse IgG1 단일클론 항체로 인간 시료에 반응합니다. Western blot 및 ELISA에 적합하며, 고순도 Protein G 정제 및 PBS buffer에 보존됩니다. 연구용으로만 사용되며 NeuroD1 관련 신경분화 연구에 활용 가능합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| ELISA | 1:10,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 8C4H4 |
| Immunogen | Purified recombinant fragment of human NeuroD1 (AA: 26–91) expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3091033 |
Target Information
NeuroD1 is a transcriptional activator that acts as a differentiation factor during neurogenesis. It binds to the insulin gene E-box, and efficient DNA binding requires dimerization with another basic helix-loop-helix (bHLH) protein.
Defects in NEUROD1 are associated with maturity-onset diabetes of the young type VI (MODY6), a non-insulin-dependent diabetes mellitus characterized by autosomal dominant inheritance, early onset, and defective insulin secretion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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