Thermo Fisher Scientific Phospho-PDGFRB (Tyr579, Tyr581) Polyclonal Antibody
PDGFRB의 Tyr579 및 Tyr581 인산화 형태를 특이적으로 검출하는 Rabbit Polyclonal Antibody. Western blot 및 IHC(Paraffin) 적용 가능. 고순도 액상 형태로 PBS/glycerol buffer에 보관. 연구용으로만 사용.
- 카탈로그번호
- PA5118659
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific Phospho-PDGFRB (Tyr579, Tyr581) Polyclonal Antibody
Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:3,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human PDGFRB (Accession P09619), corresponding to amino acid residues around phosphorylated Tyr579 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2903159 |
Product Specific Information
Antibody detects endogenous levels of PDGF Receptor beta only when phosphorylated at Tyr579 + Tyr581.
Target Information
PDGFRB is a receptor tyrosine kinase involved in atherogenesis and cell transformation by the SIS oncogene. These growth factors act as mitogens for mesenchymal-origin cells. The receptor forms either homodimers or heterodimers depending on the bound growth factor. The PDGFRB gene is located on chromosome 5 near genes for GM-CSF and M-CSF receptor, all of which may be associated with the 5-q syndrome. A translocation between chromosomes 5 and 12 fusing PDGFRB (CD140b) and ETV6 leads to chronic myeloproliferative disorder with eosinophilia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 없음)
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.