Thermo Fisher Scientific SLAMF7 Monoclonal Antibody (OTI3B3), TrueMAB
SLAMF7 단백질을 인식하는 마우스 모노클로날 항체로, Western blot, IHC, Flow cytometry에 사용 가능. Human에 반응하며, 비결합(Unconjugated) 상태로 제공. 동결건조 형태로 -20°C 보관. 연구용으로 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Flow Cytometry (Flow) | Assay-Dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3B3 |
| Immunogen | Full length human recombinant protein of human SLAMF7 produced in HEK293T cell. Target family: CRACC (CD319), UniProt ID: Q9NQ25-1, Antigen range: 1–335 |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
SLAMF7 contains one Ig-like C2-type domain. Isoform 1 mediates NK cell activation through a SAP-independent ERK-mediated pathway and may play a role in lymphocyte adhesion. Isoform 3 does not mediate activation.
SLAMF7 is expressed in spleen, lymph node, peripheral blood leukocytes, bone marrow, small intestine, stomach, appendix, lung, and trachea. Expression is detected in NK cells, activated B-cells, and NK-cell lines, but not in promyelocytic, B-, or T-cell lines. Isoform 3 is expressed at a much lower level than isoform 1. There are three named isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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