Thermo Fisher Scientific CLN6 Polyclonal Antibody
CLN6 단백질을 인식하는 Thermo Fisher Scientific의 rabbit polyclonal antibody. Western blot, IHC, ICC/IF 등에 사용 가능. 인간, 마우스, 랫트 반응성. 고순도 Affinity chromatography 정제, 1 mg/mL 농도, 연구용 전용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human CLN6 (Accession Q9NWW5), corresponding to amino acid residues V225–L275 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2854309 |
Product Specific Information
Antibody detects endogenous levels of total CLN6.
Target Information
CLN6 is a 311-amino acid protein with 7 predicted transmembrane domains, conserved across vertebrates. It localizes to the endoplasmic reticulum and contributes to lysosomal function. Mutations in CLN6 cause variant late-onset infantile neuronal ceroid lipofuscinosis (vLINCL), a lysosomal storage disorder leading to progressive mental deterioration and blindness. CLN6 belongs to a group of eight proteins (CLN1–8) associated with neuronal ceroid lipofuscinoses (NCL).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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