Thermo Fisher Scientific CLCC1 Polyclonal Antibody
CLCC1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 Immunocytochemistry에 사용 가능. 고순도 친화 크로마토그래피 정제, 액상 형태, -20°C 보관. 연구용 전용 제품.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
- Publications: 없음
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
- Publications: 없음
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human CLCC1 (Accession Q96S66), corresponding to amino acid residues A396–D446 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2854310 |
Product Specific Information
Antibody detects endogenous levels of total CLCC1.
Target Information
Neurofibromin is a member of the GTPase-activating (GAP) class of proteins. These proteins enhance the GTPase activity of signaling G-Proteins like Ras. The NF1 gene is also classified as a tumor suppressor gene, and many studies have shown that mutations at the NF1 locus produce neurofibromas, rhabdomyosarcomas, leimyosarcomas, mental retardation, and memory deficiency. Neurofibromin has also been associated with the intermediate filaments of the cytoskeleton. NF1 is expressed at its highest levels during periods of desmosome formation, and mutations of NF1 produce variable cell sizes and morphologies.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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