Thermo Fisher Scientific GCLC Polyclonal Antibody
GCLC 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, Western blot 및 Immunocytochemistry에 적합합니다. 인간, 생쥐, 돼지, 쥐 시료에 반응하며, 액상 형태로 -20°C에서 보관합니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- PA5103134
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific GCLC Polyclonal Antibody
Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:3,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Pig, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human GCLC (Accession P48506), corresponding to amino acid residues K73–N123 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2852504 |
Product Specific Information
Antibody detects endogenous levels of total GCLC.
Target Information
Glutamate-cysteine ligase (gamma-glutamylcysteine synthetase) is the first rate-limiting enzyme of glutathione synthesis. The enzyme consists of two subunits: a heavy catalytic subunit and a light regulatory subunit. This gene encodes the catalytic subunit, while the regulatory subunit is encoded by a separate gene on chromosome 1p22–p21. Mutations in this locus are associated with hemolytic anemia due to deficiency of gamma-glutamylcysteine synthetase and susceptibility to myocardial infarction.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 없음)
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.