Thermo Fisher Scientific IPO5 Monoclonal Antibody (OTI4C3), TrueMAB
IPO5 단백질을 표적하는 Mouse monoclonal antibody로 Western blot에 적합. Human 및 Mouse 반응성. 고순도 affinity chromatography로 정제된 액상 형태. 안정적인 PBS/BSA/glycerol buffer 구성으로 -20°C 보관 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4C3 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–220 of human IPO5 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5–1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Nucleocytoplasmic transport is a signal- and energy-dependent process occurring through nuclear pore complexes embedded in the nuclear envelope. Proteins containing a nuclear localization signal (NLS) require an NLS import receptor, a heterodimer of importin alpha and beta subunits (karyopherins). Importin alpha binds the NLS-containing cargo, while importin beta docks the complex at the cytoplasmic side of the nuclear pore. In the presence of nucleoside triphosphates and the small GTP-binding protein Ran, the complex translocates into the nuclear pore and dissociates. Importin alpha enters the nucleoplasm with its cargo, and importin beta remains at the pore. Interactions between importin beta and FG repeats of nucleoporins are essential for translocation. The protein encoded by this gene is a member of the importin beta family.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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