Thermo Fisher Scientific STK38 Polyclonal Antibody
STK38 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western blot에 최적화됨. 인간 시료에 반응하며, KLH 결합 합성 펩타이드(410-439 aa)를 면역원으로 사용. 액상 형태로 제공되며, PBS(pH 7.4)에 0.09% sodium azide 포함. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide between 410–439 amino acids from the C-terminal region of human STK38 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Ammonium sulfate precipitation, Size-exclusion - Dialysis |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2196795 |
Target Information
STK38 (also known as NDR) or Nuclear Dbf2-related protein is a serine/threonine kinase in the AGC kinase family regulated by Mob proteins.
Fas and TNFα receptor stimulation activates human STK38 by promoting phosphorylation at the hydrophobic motif.
NDR acts as a novel pro-apoptotic kinase and is a key member of the RASSF1A/MST1 signaling cascade.
STK38 is crucial for the fidelity of mitotic chromosome alignment in mammalian cells.
It is incorporated into HIV-1 particles and cleaved by the HIV-1 protease.
STK38-driven centrosome duplication requires Cdk2 activity, and Cdk2-induced centrosome amplification is affected upon reduction of STK38 activity.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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