Thermo Fisher Scientific EAAT2 Polyclonal Antibody, FITC
EAAT2 단백질을 인식하는 FITC 결합 토끼 폴리클로날 항체로, Western blot, IHC, ELISA, IP에 사용 가능. 인간, 마우스, 랫트에 반응하며, 높은 특이성과 신뢰성 제공. 형광 분석 및 신경전달 연구에 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (IHC) | 1:50–1:250 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to C-terminal amino acids 550–574 of Human EAAT2 (Sequence: KVTLAANGKSADCSVEEEPWKREK) |
| Conjugate | FITC (Fluorescein Isothiocyanate) |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer, pH 7.4–7.8, with 30% glycerol, 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | –20 °C, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Excitatory amino acid transporter 2 (EAAT2) is a membrane-bound solute transporter protein responsible for clearing the excitatory neurotransmitter glutamate from the extracellular synaptic space in the central nervous system. Proper glutamate clearance is essential for synaptic activation and preventing neuronal damage from overactivation of glutamate receptors. Mutations or decreased expression of EAAT2 are associated with amyotrophic lateral sclerosis (ALS). Alternatively spliced transcript variants of this gene have been identified.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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