Thermo Fisher Scientific EAAT2 Polyclonal Antibody, Biotin
EAAT2 단백질을 인식하는 Biotin 결합 토끼 다클론 항체로, Western blot, IHC, ELISA, IP 등 다양한 응용에 적합합니다. 인간, 마우스, 랫트 시료에 반응하며, 고순도 친화 크로마토그래피 정제 및 안정한 보존용액으로 제공됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (IHC) | 1:50–1:250 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to C-terminal amino acids 550–574 of Human EAAT2 (Sequence: KVTLAANGKSADCSVEEEPWKREK) |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer, pH 7.4–7.8, with 30% glycerol, 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | –20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Excitatory amino acid transporter 2 (EAAT2) is a member of the solute transporter protein family. This membrane-bound protein is the principal transporter responsible for clearing the excitatory neurotransmitter glutamate from the extracellular space at synapses in the central nervous system. Proper glutamate clearance is essential for normal synaptic activation and to prevent neuronal damage from excessive activation of glutamate receptors. Mutations or decreased expression of EAAT2 are associated with amyotrophic lateral sclerosis (ALS). Alternatively spliced transcript variants of this gene have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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