Thermo Fisher Scientific CD14 Monoclonal Antibody (OTI3F5), TrueMAB
CD14 단백질을 인식하는 Mouse IgG1 단클론 항체로, 인간 시료에 반응합니다. IHC(P)에서 1:2000 희석으로 사용 가능하며, TrueMAB 형식으로 고순도 정제되었습니다. PBS/BSA/glycerol 완충액에 보관되며 연구용으로 적합합니다.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): Tested Dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3F5 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 20–367 of human CD14 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
CD14 is a 55 kDa GPI-anchored glycoprotein expressed on mature monocytes, macrophages, and neutrophils. It functions as a multifunctional lipopolysaccharide receptor and is found both in membrane-bound and soluble forms. CD14 interacts with lipopolysaccharide-binding protein (LBP) and plays a key role in immune responses, including neutralization of lipopolysaccharides and apoptotic cell binding. Dysregulation of CD14 is associated with infectious and inflammatory conditions such as Mycobacterium chelonae infection and croup. Alternative splicing results in multiple transcript variants encoding the same isoform.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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