Thermo Fisher Scientific PHGDH Monoclonal Antibody (OTI9C2)
PHGDH 단백질을 인식하는 Thermo Fisher의 단클론 항체로, Western blot과 IHC(P) 등에 사용 가능. 사람, 생쥐, 쥐 반응성. 액상 형태, 1 mg/mL 농도. PBS 기반 버퍼에 BSA와 글리세롤 포함. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI9C2 |
| Immunogen | Full length human recombinant protein of PHGDH produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2725015 |
Target Information
The PHGDH gene encodes an enzyme involved in the early steps of L-serine synthesis in animal cells.
L-serine is required for the synthesis of D-serine and other amino acids.
The enzyme requires NAD/NADH as a cofactor and forms homotetramers for activity.
Mutations in this gene have been associated with congenital microcephaly, psychomotor retardation, and other symptoms.
Multiple alternatively spliced transcript variants have been identified, though the full-length nature of most is not known.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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