Thermo Fisher Scientific PHGDH Monoclonal Antibody (OTI5C4)
PHGDH 단백질을 인식하는 단클론 항체로 Western blot, IHC, ICC/IF에 사용 가능. Human, Mouse, Rat 시료에 반응하며, 고순도 Affinity Chromatography로 정제됨. 1 mg/mL 농도의 액상 형태로 -20°C 보관.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5C4 |
| Immunogen | Full length human recombinant protein of PHGDH produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2725014 |
Target Information
The PHGDH gene encodes an enzyme involved in the early steps of L-serine synthesis in animal cells. L-serine is necessary for the synthesis of D-serine and other amino acids. The enzyme requires NAD/NADH as a cofactor and functions as a homotetramer. Mutations in this gene have been linked to congenital microcephaly, psychomotor retardation, and other neurological symptoms. Multiple alternatively spliced transcript variants exist, though many full-length forms remain uncharacterized.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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