Thermo Fisher Scientific LEMD2 Polyclonal Antibody
LEMD2 단백질을 검출하기 위한 Rabbit Polyclonal 항체로, WB 및 ICC/IF에 적합합니다. 인간 및 생쥐 시료에 반응하며, 고순도 항원 친화 크로마토그래피로 정제되었습니다. 세포핵 구조 연구 및 근육 질환 관련 연구에 활용 가능합니다.
- 카탈로그번호
- PA534397
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific LEMD2 Polyclonal Antibody
Applications
Western Blot (WB)
- Tested Dilution: 1–2 µg/mL
Immunocytochemistry (ICC/IF)
- Tested Dilution: 2.5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A 16 amino acid synthetic peptide near the center of human LEMD2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long term storage store at -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2551749 |
Product Specific Information
- A suggested positive control is 293 cell lysate.
- PA5-34397 can be used with blocking peptide PEP-1439.
Target Information
The LEM (lamina-associated polypeptide-emerin-MAN1) domain is a motif shared by lamin-interacting proteins of the inner nuclear membrane (INM) and nucleoplasm.
LEMD2 (LEM domain-containing protein 2) is a lamina-associated protein in the INM involved in nuclear structure organization. It contains an N-terminal LEM motif, two transmembrane domains, and a MAN1-Src1p C-terminal (MSC) domain.
LEMD2 is a truncated paralog of MAN1, lacking the MAN1-specific C-terminal RNA-recognition motif, but like MAN1, it is required for myogenic differentiation.
Mutations in LEMD2 are thought to be among possible causes of muscle disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.