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Thermo Fisher Scientific FZD7 Polyclonal Antibody
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Thermo Fisher Scientific의 FZD7 Polyclonal Antibody는 마우스 FZD7 단백질을 인식하는 Rabbit IgG 항체로, Western blot에 최적화되어 있습니다. 합성 펩타이드 면역원으로 제작되었으며, 고순도의 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용 가능합니다.
- 판매단위
- pk
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마지막 업데이트 2025. 08. 04. 오후 12:44
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Thermo Fisher Scientific PA14137 FZD7 Polyclonal Antibody 100 ug pk판매 단위 pk ·
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630,500원VAT 포함 693,550원
Thermo Fisher Scientific · Thermo Fisher Scientific FZD7 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues M(1) R G P G T A A S H S P C(12) of mouse Frizzled |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long-term storage, store at -20°C. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2109395 |
Product Specific Information
- PA1-4137 detects mouse Frizzled.
- Successfully used in Western blot procedures.
- Detects a ~40 kDa protein representing mouse Fz in mouse pancreas lysate.
- Immunogen sequence is 91% conserved in rat.
Target Information
Members of the frizzled gene family encode 7-transmembrane domain proteins that act as receptors for Wnt signaling proteins.
FZD7 protein includes:
- N-terminal signal sequence
- 10 cysteine residues typical of the cysteine-rich extracellular domain
- 7 transmembrane domains
- Intracellular C-terminal tail with PDZ domain-binding motif
FZD7 gene expression may downregulate APC function and enhance beta-catenin-mediated signaling in poorly differentiated human esophageal carcinomas.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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