Thermo Fisher Scientific TGIF Polyclonal Antibody
TGIF1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody입니다. Western blot 및 Immunocytochemistry에 적합하며, 고순도 Affinity chromatography로 정제되었습니다. PBS/glycerol 버퍼에 보관되며 연구용으로 사용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:3,000
- Publications: [참고 문헌]
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
- Publications: [참고 문헌]
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human TGIF1 (Accession Q15583), corresponding to amino acid residues G324–Q374 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2852263 |
Product Specific Information
Antibody detects endogenous levels of total TGIF1.
Target Information
TGIF is a member of the three-amino acid loop extension (TALE) superclass of atypical homeodomains. TALE homeobox proteins are highly conserved transcription regulators. This homeodomain binds to a retinoid X receptor responsive element from the cellular retinol-binding protein II promoter. TGIF acts as a transcriptional co-repressor of SMAD2 and may participate in nuclear signaling during development and adulthood. Mutations in TGIF are associated with holoprosencephaly type 4, a structural brain anomaly.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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