Thermo Fisher Scientific GREM1 Monoclonal Antibody (2D1)
GREM1 단백질을 인식하는 Mouse IgG2a 단클론 항체로 Western blot과 ELISA에 사용 가능. 인간 시료에 반응하며 PBS 버퍼에 보관. 연구용으로만 사용 가능. Affinity chromatography로 정제된 고품질 액상 항체.
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Applications
Western Blot (WB)
- Tested Dilution: 1–5 µg/mL
ELISA
- Tested Dilution: 1 ng/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2D1 |
| Immunogen | GREM1 (NP_037504, 75–184 a.a.) partial recombinant protein with GST tag (MW of GST tag: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
ESSQEALHVT ERKYLKRDWC KTQPLKQTIH EEGCNSRTII NRFCYGQCNS FYIPRHIRKE EGSFQSCSFC KPKKFTTMMV TLNCPELQPP TKKKRVTRVK QCRCISIDLD
Target Information
In Xenopus, Gremlin belongs to a novel gene family that acts as BMP antagonists in embryonic explants.
The human homolog of Drm/Gremlin (CKTFS1B1) is localized on chromosome 15q13–q15. DRM-specific mRNA is expressed in various human tissues, including brain, ovary, intestine, and colon.
Down-regulation of DRM has been associated with tumor progression, suggesting that human DRM may play an important role in neuroembryological development and carcinogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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