Thermo Fisher Scientific ACTR1A Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 187-376 of human ACTR1A (NP_0057271) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:ACTR1A,uniProtId:P61163-1,ncbiNodeId:9606,antigenRange:187-376,antigenLength:376,antigenImageFileName:PA5-93024_ACTR1A_P61163-1_Rabbit.svg,antigenImageFileNamePDP:PA5-93024_ACTR1A_P61163-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.44 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2806594

Product Specific Information

Immunogen sequence: GRDVSRFLRL YLRKEGYDFH SSSEFEIVKA IKERACYLSI NPQKDETLET EKAQYYLPDG STIEIGPSRF RAPELLFRPD LIGEESEGIH EVLVFAIQKS DMDLRRTLFS NIVLSGGSTL FKGFGDRLLS EVKKLAPKDV KIRISAPQER LYSTWIGGSI LASLDTFKKM WVSKKEYEED GARSIHRKTF; Positive Samples: MCF7, Mouse skeletal muscle, Mouse spleen, Mouse lung, Rat brain; Cellular Location: Cytoplasm, centrosome, cytoskeleton, microtubule organizing center

Target Information

This gene encodes a 42.6 kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 8-13 copies per dynactin molecule, and is the most abundant molecule in the dynactin complex. It is an actin-related protein, and is approximately 60% identical at the amino acid level to conventional actin.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.