Thermo Fisher Scientific KCNN3 Polyclonal Antibody
KCNN3 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, 인간 및 설치류 등 다양한 종에 반응합니다. Western blot과 IHC(P) 실험에 적합하며, 고순도 친화 크로마토그래피로 정제된 액상 항체입니다. 연구용으로만 사용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.2–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:300–1:600 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the C-terminal of human KCNN3 (aa 642–691) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2576733 |
Product Specific Information
Peptide sequence:
ITELNDRSED LEKQIGSLES KLEHLTASFN SLPLLIADTL RQQQQQLLSA
Sequence homology:
Cow: 100%
Dog: 100%
Guinea Pig: 100%
Horse: 93%
Human: 100%
Mouse: 100%
Rabbit: 100%
Rat: 100%
Target Information
Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and mediated by different calcium-activated potassium channels.
KCNN3, a member of the KCNN family of potassium channel genes, encodes a protein activated before membrane hyperpolarization and is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. The encoded protein is an integral membrane protein that forms a voltage-independent calcium-activated channel with three other calmodulin-binding subunits.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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