Thermo Fisher Scientific KCNN1 Polyclonal Antibody
KCNN1 단백질을 인식하는 Rabbit Polyclonal 항체로, Western Blot에 최적화되어 있습니다. 인간 단백질에 반응하며, C-말단 펩타이드(aa 441-490)를 면역원으로 사용했습니다. Protein A로 정제되었으며, PBS와 2% sucrose buffer에 보관됩니다.
- 판매단위
- pk
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Applications
- Western Blot (WB): Tested at 1.25 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the C-terminal of human KCNN1 (aa 441-490) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2606228 |
Product Specific Information
- Peptide sequence: KIEQGKLNDQ ANTLTDLAKT QTVMYDLVSE LHAQHEELEA RLATLESRLD
- Sequence homology:
- Cow: 93%
- Dog: 93%
- Guinea Pig: 79%
- Horse: 92%
- Human: 100%
- Pig: 93%
- Rat: 85%
Target Information
Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and influence neuronal firing patterns. Each component of the AHP is kinetically distinct and mediated by different calcium-activated potassium channels.
The KCNN1 gene encodes an integral membrane protein that forms a voltage-independent calcium-activated channel with three other calmodulin-binding subunits. It regulates neuronal excitability by contributing to the slow component of synaptic AHP and is a member of the KCNN family of potassium channels.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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