Thermo Fisher Scientific MEPE Polyclonal Antibody
Human MEPE 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(P)에서 1:50~1:200 희석 비율로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS 및 40% 글리세롤 버퍼에 보관. 골세포 및 종양 세포주에서 MEPE 발현 연구에 적합.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human MEPE. Recombinant protein control fragment (Product #RP-96692) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2643876 |
Product Specific Information
- Immunogen sequence:
REENGGNTIG TRDETAKEAD AVDVSLVEGS NDIMGSTNFK ELPGREGNRV DAGSQNAHQG KVEFHYPPAP SKEKRKEGSS DAAESTNYNE IPK - Highest antigen sequence identity:
- Mouse: 61%
- Rat: 67%
Target Information
Matrix extracellular phosphoglycoprotein (MEPE), also known as osteoblast/osteocyte factor 45 (OF45), is a member of the small integrin-binding ligand N-linked glycoprotein (SIBLING) family.
MEPE promotes renal phosphate excretion and modulates mineralization. It can be phosphorylated by secreted protein kinases.
MEPE is expressed in osteoblasts, osteocytes, and odontoblasts, and the expression has also been reported in numerous human tumor cell lines.
It is a 525-amino acid protein with a calculated molecular weight of 58 kDa.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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