Thermo Fisher Scientific MEPE Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human MEPE. Recombinant protein control fragment (Product #RP-96693). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:MEPE,uniProtId:Q9NQ76-1,ncbiNodeId:9606,antigenRange:180-275,antigenLength:525,antigenImageFileName:PA5-58206_MEPE_Q9NQ76-1_Rabbit.svg,antigenImageFileNamePDP:PA5-58206_MEPE_Q9NQ76-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.4 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2643877

Product Specific Information

Immunogen sequence: IPASMNYAKA HSKDKKKPQR DSQAQKSPVK SKSTHRIQHN IDYLKHLSKV KKIPSDFEGS GYTDLQERGD NDISPFSGDG QPFKDIPGKG EATGPD

Highest antigen sequence identity to the following orthologs: Mouse - 53%, Rat - 48%.

Target Information

Matrix extracellular phosphoglycoprotein (MEPE), also known as osteoblast/osteocyte factor 45 (OF45), is a member of the small integrin-binding ligand N-linked glycoprotein (SIBLING) family. MEPE promotes renal phosphate excretion and modulates mineralization. It can be phosphorylated by secreted protein kinases. MEPE is expressed in osteoblasts, osteocytes and odontoblasts, and the expression has also been reported in numerous human tumor cell lines. It is a 525-amino acid protein with a calculated molecular weight of 58 kDa.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.