Thermo Fisher Scientific CD9 Polyclonal Antibody

Applications

• Western Blot (WB): 1:500–1:1,000 dilution

Product Specifications

Product Specific Information

Purity is >95% by SDS-PAGE.

Target Information

CD9 antigen is a glycoprotein expressed on the surface of developing B lymphocytes, platelets, monocytes, eosinophils, basophils, stimulated T lymphocytes, and by neurons and glial cells in the peripheral nervous system.
CD9 belongs to the tetraspanin family, transversing the membrane four times. In pre-B cells and platelets, CD9 regulates cell activation and aggregation through association with integrins CD41/CD61 (GPIIb/GPIIIa).
It is involved in cell motility, osteoclastogenesis, neurite outgrowth, myotube formation, and sperm-egg fusion. CD9 plays roles in cell attachment and proliferation, and assists in MHC II molecule association on dendritic cell membranes for effective T cell stimulation.
CD9 functions in differentiation, adhesion, and signal transduction, and its expression is critical for suppression of cancer cell motility and metastasis. It is considered a metastasis suppressor in solid tumors.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.