Thermo Fisher Scientific Alpha-Smooth Muscle Actin Monoclonal Antibody (1H8)
Alpha-Smooth Muscle Actin 단클론 항체(1H8)는 Human, Mouse, Rat 등 다양한 종에서 ACTA2 단백질 검출에 사용됩니다. WB, IHC, ICC, Flow, ELISA 등 다중 응용 가능하며, 고품질 모노클론 항체로 세포골격 및 근육 수축 연구에 적합합니다.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:2,000 | - |
| Immunohistochemistry (IHC) | - | View 1 publication |
| Immunocytochemistry (ICC/IF) | 1:200–1:1,000 | - |
| Flow Cytometry (Flow) | 1:200–1:400 | View 1 publication |
| ELISA | 1:10,000 | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate, Rat |
| Published Species | Mouse |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1H8 |
| Immunogen | Purified recombinant fragment of human ACTA2 expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not determined |
| Storage Buffer | Ascites |
| Contains | 0.03% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_11153718 |
Product Specific Information
MA5-15805 targets ACTA2 in indirect ELISA, FACS, IF, and WB applications and shows reactivity with Human, Mouse, Non-human primate, and Rat samples.
The immunogen is a purified recombinant fragment of human ACTA2 expressed in E. coli.
MA5-15805 detects ACTA2, which has a predicted molecular weight of approximately 42 kDa.
Target Information
Smooth Muscle Actin belongs to the actin family of proteins, which are highly conserved and play essential roles in cell motility, structure, and integrity.
Alpha, beta, and gamma actin isoforms have been identified:
- Alpha actin is a major component of the contractile apparatus.
- Beta and gamma actins regulate cell motility.
Smooth muscle actin is an alpha actin found in skeletal muscle and smooth muscle tissues such as vessel walls, gut wall, myometrium, and myoepithelial cells.
Defects in the smooth muscle actin gene can cause familial thoracic aortic aneurysm type 6.
Alpha-smooth muscle actin is abundant in vascular and visceral smooth muscle cells, and can also appear in fibroblastic stress fibers during wound healing or fibrocontractive conditions.
Multiple alternatively spliced variants of smooth muscle actin have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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