Thermo Fisher Scientific Aurora A Monoclonal Antibody (1F8)
Aurora A 단백질을 인식하는 Mouse monoclonal 항체로, Human, Rat, Non-human primate 시료에 반응합니다. Western blot, ICC/IF, Flow cytometry, ELISA에 적합하며, 암 연구 및 세포주기 조절 연구에 활용됩니다.
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- MA515803
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:2,000 | View 1 publication |
| Immunocytochemistry (ICC/IF) | 1:200–1:1,000 | - |
| Flow Cytometry (Flow) | 1:200–1:400 | - |
| ELISA | 1:10,000 | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Non-human primate, Rat |
| Published Species | Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1F8 |
| Immunogen | Purified recombinant fragment of human AURKA expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not determined |
| Storage Buffer | Ascites |
| Contains | 0.03% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_11154080 |
Product Specific Information
MA5-15803 targets AURKA in indirect ELISA, FACS, IF, and WB applications, and shows reactivity with Human, Non-human primate, and Rat samples.
The immunogen is a purified recombinant fragment of human AURKA expressed in E. coli.
MA5-15803 detects AURKA with a predicted molecular weight of approximately 48 kDa.
Target Information
AURKA (Aurora A) is a serine/threonine kinase that regulates mitosis by association with centrosomes. Overexpression of AURKA is observed in many types of cancer. Aurora A plays a role in cell cycle regulation during anaphase and/or telophase, associated with the centrosome/spindle pole region during chromosome segregation.
It is a key factor in tumor development and progression and is overexpressed in cancers such as breast, ovarian, and colorectal.
Tissue specificity: Highly expressed in testis, weakly in skeletal muscle, thymus, and spleen.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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