Thermo Fisher Scientific SCAMP2 Polyclonal Antibody
SCAMP2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody입니다. Western blot 및 IHC(P)에서 검증되었으며, 인간, 마우스, 랫트에 반응합니다. 항원 친화 크로마토그래피로 정제되었으며, 연구용으로 적합합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 0.04–0.4 µg/mL
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human SCAMP2. Recombinant protein control fragment (Product #RP-91154) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2646982 |
Product Specific Information
- Immunogen sequence:
QRVHSLYRRT GASFQQAQEE FSQGIFSSRT FHRAASSAAQ GAFQ - Highest antigen sequence identity to orthologs:
Mouse – 89%, Rat – 86%
Target Information
Secretory carrier membrane proteins (SCAMPs) are components of post-Golgi membranes involved in membrane trafficking.
In fibroblasts, SCAMPs are concentrated in compartments related to receptor recycling and endocytosis.
In neurons, SCAMPs associate with synaptic vesicles, secretion granules, and transporter vesicles.
SCAMPs contain four transmembrane regions and a cytoplasmic tail.
Among five known SCAMPs, SCAMPs 1–3 have N-terminal NPF repeats interacting with EH domain proteins for vesicle budding.
SCAMPs 4 and 5 lack these repeats. SCAMPs 1–4 are ubiquitously expressed, while SCAMP 5 is brain-specific and expressed late in development, coinciding with mature synapse formation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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