
Thermo Fisher Scientific mature NT3 Polyclonal Antibody
Rabbit polyclonal antibody recognizing mature NT-3 protein. Validated for WB and IHC in human, mouse, and rat. Lyophilized form, reconstitutable in sterile water. Suitable for neurobiology research on neuronal survival and differentiation.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:300–1:2,000 | – |
| Immunohistochemistry (IHC) | 1:300–1:2,000 | – |
| Miscellaneous PubMed (Misc) | – | View 3 publications |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide from amino acid region 140–200 of human NT3 conjugated to an immunogenic carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4 °C short term. For long-term storage, store at –20 °C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water.
- Centrifuge to remove any insoluble material.
- The peptide is homologous in many other species including rat and mouse.
- Specificity: mature NT-3.
Target Information
The NT-3 (Neurotrophin-3) protein is part of the neurotrophin family that regulates survival and differentiation of mammalian neurons. It is closely related to nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF). NT-3 may contribute to maintenance of the adult nervous system and neuronal development during embryogenesis. NTF3-deficient mice show severe limb movement defects. The mature peptide sequence is identical across mammals including human, pig, rat, and mouse.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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