Thermo Fisher Scientific mature NT3 Polyclonal Antibody
Rabbit polyclonal antibody recognizing mature NT-3 protein. Validated for WB and IHC in human, mouse, and rat. Lyophilized form, reconstitutable in sterile water. Suitable for studies on neuronal survival and differentiation.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 10–50 µg/mL | – |
| Immunohistochemistry (IHC) | 10–50 µg/mL | – |
| Miscellaneous (PubMed) | – | View 2 publications |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from amino acid region 140–200 of human NT3 conjugated to an immunogenic carrier protein. |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not determined |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4 °C short term. For long-term storage, store at −20 °C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 500 µL of sterile water.
- Centrifuge to remove any insoluble material.
- The peptide is homologous in many other species including rat and mouse.
- Specificity: mature NT-3.
Target Information
The protein encoded by the NTF3 gene is a member of the neurotrophin family that controls survival and differentiation of mammalian neurons. It is closely related to nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF). This protein may be involved in maintenance of the adult nervous system and neuronal development in the embryo. NTF3-deficient mice show severe limb movement defects. The mature peptide is identical across mammals including human, pig, rat, and mouse.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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