Thermo Fisher Scientific HLA-DR/DP/DQ Chimeric Recombinant Rabbit Monoclonal Antibody (F3.3)
HLA-DR/DP/DQ 클래스 II 분자를 인식하는 재조합 토끼 단일클론 항체로, 인간 시료에 반응합니다. Western blot과 유세포분석(Flow Cytometry)에 적합하며, HEK293 발현 시스템에서 생산되었습니다. Protein A로 정제된 액상 형태로 제공됩니다.
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Thermo Fisher Scientific HLA-DR/DP/DQ Chimeric Recombinant Rabbit Monoclonal Antibody (F3.3)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.01 µg/mL |
| Flow Cytometry (Flow) | 10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | F3.3 |
| Immunogen | Proprietary sequence |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3074278 |
Product Specific Information
Specificity: Recognises anti-class II HLA molecules.
Target Information
MHC class II molecules are transmembrane glycoproteins composed of an alpha chain (36 kDa) and a beta chain (27 kDa). They are expressed primarily on antigen-presenting cells such as B lymphocytes, monocytes, macrophages, thymic epithelial cells, and activated T lymphocytes.
Three loci—DR, DQ, and DP—encode the major expressed products of the human class II region.
Human MHC class II molecules bind intracellularly processed peptides and present them to T-helper cells, playing a critical role in initiating the immune response.
HLA and MHC antibodies are crucial tools in Immunopeptidomics, enabling identification and characterization of neoantigens through high-performance liquid chromatography coupled with tandem mass spectrometry.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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