Thermo Fisher Scientific SARS-CoV-2 Spike Protein S1/S2 VHH-8His-Cys-tag Recombinant Alpaca Monoclonal Antibody (SAA0871)
SARS-CoV-2 Spike Protein S1/S2를 인식하는 알파카 유래 재조합 단일클론 항체. ELISA 등 연구용 분석에 적합하며, CHO 세포 발현 시스템 사용. 금속 킬레이트 크로마토그래피로 정제된 고순도 항체. 장기 보관 시 -20°C에서 안정적 유지.
- 판매단위
- pk
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Thermo Fisher Scientific SARS-CoV-2 Spike Protein S1/S2 VHH-8His-Cys-tag Recombinant Alpaca Monoclonal Antibody (SAA0871)
Applications
- ELISA (Assay-dependent)
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Virus |
| Host / Isotype | Alpaca / VHH |
| Expression System | CHO cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | SAA0871 |
| Immunogen | Recombinant SARS-CoV-2 S protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Metal-chelate chromatography |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
Product Specific Information
- Compatible with Direct ELISA
Target Information
SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2), also known as 2019-nCoV, is a virus that causes illnesses ranging from mild cold-like symptoms to severe respiratory distress and death.
The CoV Spike (S) protein plays a crucial role in viral attachment, fusion, and entry, serving as a key target for antibody, inhibitor, and vaccine development.
The receptor-binding domain (RBD) within the S1 subunit binds strongly to human and bat ACE2 receptors, exhibiting higher affinity than SARS-CoV RBD.
S1 contains the RBD responsible for ACE2 binding, while S2 mediates membrane fusion.
SARS-CoV-2 S protein consists of 1273 amino acids: a signal peptide (1–13), S1 subunit (14–685), and S2 subunit (686–1273). The extracellular domain (S-ECD) represents the Spike protein’s functional region.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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