Thermo Fisher Scientific SARS-CoV-2 Spike Protein S1/S2 VHH-8His-Cys-tag Recombinant Alpaca Monoclonal Antibody (SAA0885)
SARS-CoV-2 Spike 단백질을 표적으로 하는 알파카 유래 재조합 단일클론 항체입니다. ELISA 등 연구용 분석에 적합하며, CHO 세포에서 발현된 VHH 형식입니다. 금속 킬레이트 크로마토그래피로 정제되었으며, 보존제가 없는 PBS 용액 형태로 제공됩니다.
- 판매단위
- pk
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Thermo Fisher Scientific SARS-CoV-2 Spike Protein S1/S2 VHH-8His-Cys-tag Recombinant Alpaca Monoclonal Antibody (SAA0885)
Applications
- ELISA (Assay-dependent)
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Virus |
| Host / Isotype | Alpaca / VHH |
| Expression System | CHO cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | SAA0885 |
| Immunogen | Recombinant SARS-CoV-2 S protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Metal-chelate chromatography |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
Product Specific Information
- Compatible with Direct ELISA
Target Information
SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2), also known as 2019-nCoV, causes illnesses ranging from mild cold-like symptoms to severe respiratory distress and death.
The CoV Spike (S) protein is critical for viral attachment, fusion, and entry, serving as a major target for antibody and vaccine development.
The Spike protein receptor-binding domain (RBD, S-RBD) binds strongly to human and bat ACE2 receptors, exhibiting higher affinity than SARS-CoV RBD.
S1 contains the RBD that specifically binds to ACE2 receptors on target cells.
SARS-CoV-2 Spike protein is 1273 amino acids long, consisting of:
- Signal peptide (aa 1–13)
- S1 subunit (aa 14–685)
- S2 subunit (aa 686–1273)
These regions are responsible for receptor binding and membrane fusion. The S-ECD represents the extracellular domain of the Spike protein.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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