
Thermo Fisher Scientific Phospho-PKA alpha/beta (Thr197) Recombinant Superclonal Antibody (6HCLC)
PKA alpha/beta Thr197 인산화형을 인식하는 Recombinant Superclonal 항체로, 높은 특이성과 재현성을 제공합니다. WB 및 ICC/IF에 적합하며, 다양한 종(인간, 마우스 등)에 반응합니다. Protein A 정제, 0.5 mg/mL 농도, 4°C 보관 권장.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse, Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | Expi293 |
| Class | Recombinant Superclonal |
| Type | Antibody |
| Clone | 6HCLC |
| Immunogen | Chemically synthesized phosphopeptide derived from a region of human PKA (PRKACA, PRKACB) around Thr197 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2633194 |
Product Specific Information
This antibody is predicted to react with Monkey, Rat, Mouse, Bovine, and Pig.
Recombinant rabbit Superclonal™ antibodies are unique offerings from Thermo Fisher Scientific. They consist of multiple different recombinant monoclonal antibodies, combining the sensitivity of polyclonal antibodies with the specificity and consistency of monoclonal antibodies.
Each lot contains a defined mixture of light and heavy chains, ensuring reproducibility and eliminating biological variability.
Note: Formerly called “Recombinant polyclonal antibody”, this product is now rebranded as “Recombinant Superclonal™ antibody”. The physical product and performance remain unchanged.
Target Information
cAMP is a signaling molecule involved in numerous cellular processes. It activates cAMP-dependent protein kinase (AMPK), which phosphorylates target proteins to propagate signaling.
Inactive AMPK exists as a tetramer (two regulatory and two catalytic subunits). Upon cAMP binding, it dissociates into regulatory dimers and free catalytic subunits.
PRKACB, a catalytic subunit of AMPK, belongs to the Ser/Thr protein kinase family and plays a critical role in cAMP-mediated signaling.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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