Thermo Fisher Scientific Calpain 1 Monoclonal Antibody (CAPN1/1530)
Calpain 1 단백질을 인식하는 Mouse 모노클로날 항체로, IHC(P), IHC(PFA), ELISA에 사용 가능. 인간 시료 반응성, Protein A/G 정제, PBS 버퍼에 0.05% BSA 포함. 연구용으로만 사용.
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Applications
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| ELISA | 2–4 µg/mL |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | CAPN1/1530 |
| Immunogen | Recombinant full-length human CAPN1 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Calpains, including Calpain 1 (CAPN1), are calcium-activated neutral proteases that function as nonlysosomal, intracellular cysteine proteases. Mammalian calpains include ubiquitous, stomach-specific, and muscle-specific forms. The ubiquitous enzymes are heterodimers composed of distinct large catalytic subunits and a common small regulatory subunit. The CAPN1 gene encodes the large subunit of the ubiquitous enzyme calpain 1. Multiple transcript variants encoding two isoforms have been identified. Diseases associated with CAPN1 include Spastic Paraplegia 76, Autosomal Recessive, and Spasticity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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