Thermo Fisher Scientific NF-kB p65/RELA Monoclonal Antibody (PCRP-RELA-2B6)
NF-kB p65/RELA 단백질을 인식하는 Mouse monoclonal 항체로, Human 및 Mouse 시료에 반응합니다. Western blot, ICC/IF, Flow cytometry, Peptide array 등 다양한 응용에 적합하며, Protein A/G로 정제된 고순도 항체입니다. 연구용으로만 사용됩니다.
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- 5970-MSM2-P1ABX
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg/10⁶ cells |
| Peptide Array (Array) | Assay-dependent |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | PCRP-RELA-2B6 |
| Immunogen | Recombinant full-length human RELA protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
This antibody is predicted to react with Rat.
Target Information
Nuclear factor kB p65 (NF-kB p65) is encoded by the RELA gene and located on chromosome 11 in humans. NF-kB p65, also known as RelA, belongs to the Rel family of proteins and forms part of the NF-kB complex (Nuclear factor kappa-light-chain-enhancer of activated B cells). It heterodimerizes with subunits such as p50 or p52. Upon TNF-α receptor activation, IKK phosphorylates IκB, leading to its proteasomal degradation and subsequent activation of NF-kB. NF-kB p65 plays a crucial role in the transcription of the immunoglobulin kappa gene in mature B-lymphoid cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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