Thermo Fisher Scientific PTH1R Recombinant Rabbit Monoclonal Antibody (1G7)
PTH1R 단백질을 인식하는 토끼 유래 재조합 단일클론 항체. Western blot에 적합하며, 고특이성과 재현성을 제공. HEK293 세포에서 발현, Affinity chromatography로 정제됨. 연구용으로만 사용 가능.
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Applications and Tested Dilution
- Western Blot (WB): 1:500–1:5,000
- This antibody has been tested in direct-ELISA
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 1G7 |
| Immunogen | A synthesized peptide derived from human Parathyroid Hormone Receptor 1 (PTH1R, UniProt ID: Q03431-1, antigen range: 49–163) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol, 150 mM NaCl |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Wet ice |
| RRID | AB_2898210 |
Target Information
Parathyroid hormone receptor 1 (PTH1R) is a member of the G-protein coupled receptor family. It serves as a receptor for parathyroid hormone (PTH) and parathyroid hormone-like hormone (PTHLH). The receptor activity is mediated by G proteins that activate adenylyl cyclase and a phosphatidylinositol-calcium second messenger system.
Defects in this receptor are associated with Jansen’s metaphyseal chondrodysplasia (JMC), chondrodysplasia Blomstrand type (BOCD), and enchondromatosis.
PTH1R expression has been reported in bone, breast, brain, colon, GI tract, kidney, liver, placenta, skin, umbilical cord, and uterus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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