Thermo Fisher Scientific SMC1 Recombinant Rabbit Monoclonal Antibody (8C11)
SMC1 단백질을 표적으로 하는 재조합 토끼 단클론 항체로, WB, IHC, ICC 등 다양한 응용에 적합합니다. HEK293 세포에서 발현되었으며, 고순도 친화 크로마토그래피로 정제되었습니다. 인간, 생쥐, 랫트 시료에 반응하며, 연구용으로만 사용 가능합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:5,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 5 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 8C11 |
| Immunogen | A synthesized peptide derived from human SMC1 (1100–1233aa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.21 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol, 150 mM NaCl |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Wet ice |
| RRID | AB_2898204 |
Product Specific Information
This antibody has been tested in direct-ELISA.
Target Information
Structural Maintenance of Chromosomes (SMC) family proteins play critical roles in various nuclear events that require structural changes of chromosomes, including mitotic chromosome organization, DNA recombination and repair, and global transcriptional repression. These chromosomal proteins are conserved in eukaryotes and defects can lead to mitotic chromosome segregation errors. SMC1 and SMC3 form a heterodimeric complex required for metaphase progression and sister chromatid cohesion. Mutations in the gene can cause Cornelia de Lange syndrome 2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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