
Thermo Fisher Scientific MAP2K3 Monoclonal Antibody (OTI5D7), TrueMAB
MAP2K3 단백질을 인식하는 Thermo Fisher Scientific의 단클론 항체로, WB, IHC, ICC/IF에 적합합니다. 인간 및 개 시료 반응성이 있으며, 고순도 친화 크로마토그래피 정제 제품입니다. 연구용으로만 사용되며, 안정적인 동결건조 제형으로 보관이 용이합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:200–1:4000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:150
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Dog, Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5D7 |
| Immunogen | Full length human recombinant protein of human MAP2K3 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step.
Recommended product: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL (Product #89882)
Target Information
MAP2K3 (MEK3) is a dual-specificity protein kinase involved in cellular signal transduction and glucose transporter expression.
It phosphorylates and activates MAPK14/p38-MAPK, can be activated by insulin, and is linked to oncogenic transformation via RAS expression.
Inhibition of MAP2K3 is associated with the pathogenesis of Yersinia pseudotuberculosis.
Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported for MEK3.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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