Thermo Fisher Scientific RUNX2 Polyclonal Antibody
RUNX2 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot에 적합합니다. Rat 시료에 반응하며 RUNX2 관련 골형성 연구에 활용됩니다. Affinity chromatography로 정제되었으며, PBS(2% sucrose) 버퍼에 보관됩니다.
- 카탈로그번호
- PA568508
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific RUNX2 Polyclonal Antibody
Applications and Tested Dilution
- Western Blot (WB): 0.2–1.0 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to a region of rat RUNX2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2689056 |
Product Specific Information
This target displays homology in the following species:
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rat: 100%; Zebrafish: 100%.
Target Information
RUNX2 is a nuclear protein belonging to the RUNX family of transcription factors, characterized by a Runt DNA-binding domain. It is essential for both membranous and endochondral bone formation. RUNX2 regulates osteoblastic differentiation and skeletal morphogenesis, acting as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression.
The protein binds DNA as a monomer or as part of a heterodimeric complex with higher affinity. It plays a key role in enhancing TGFBR1 expression in osteoblasts and cooperates with DLX5 or related factors to activate osteoblast-specific gene expression. Mutations in RUNX2 are associated with bone development disorders such as cleidocranial dysplasia (CCD).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.